Organonitrogen Compounds
Cambridge Isotope Laboratories 2 4 4 6-TetraBDE (BDE-75) (unlabeled) 50 ug/mL in nonane 1 2 mL
2 4 4 6-TetraBDE (BDE-75) (unlabeled) 50 ug/mL in nonane 1 2 mL
Apexbio Technology LLC KW 2449 1000669-72-6 10mM (in 1mL DMSO)
KW 2449 (CAS 1000669-72-6) is a multi-targeted kinase inhibitor with potent activity against FLT3 (IC50 6 6 nM) ABL (14 nM) Aurora kinases (4 nM) and FGFR (48 nM) It inhibits both wild-type and T315I-mutated ABL tyrosine kinase In vitro KW 2449 disrupts proliferation through modulation of distinct signaling pathways it downregulates FLT3/STAT5 phosphorylation and induces G1-phase arrest and apoptosis in FLT3-mutated leukemia cells while promoting G2/M arrest via reduced histone H3 phosphorylation in FLT3 wild-type cells KW 2449 is applied in research investigating kinase-driven leukemias and resistance mechanisms to targeted therapies
eMolecules 870-50-8 | Di-tert-butyl azodicarboxylate | Oakwood Chemicals | MFCD00015001 | 230.264 | C10H18N2O4 | 97.000 | CC(C)(C)OC(=O)\N=N\C(=O)OC(C)(C)C | 1g | 480137659
Di-tert-butyl azodicarboxylate | Oakwood Chemicals | 870-50-8 | MFCD00015001 | 230.264 | C10H18N2O4 | 97.000 | CC(C)(C)OC(=O)\N=N\C(=O)OC(C)(C)C | 1g | 480137659
Apexbio Technology LLC KW 2449 1000669-72-6 10mg
KW 2449 (CAS 1000669-72-6) is a multi-targeted kinase inhibitor with potent activity against FLT3 (IC50 6 6 nM) ABL (14 nM) Aurora kinases (4 nM) and FGFR (48 nM) It inhibits both wild-type and T315I-mutated ABL tyrosine kinase In vitro KW 2449 disrupts proliferation through modulation of distinct signaling pathways it downregulates FLT3/STAT5 phosphorylation and induces G1-phase arrest and apoptosis in FLT3-mutated leukemia cells while promoting G2/M arrest via reduced histone H3 phosphorylation in FLT3 wild-type cells KW 2449 is applied in research investigating kinase-driven leukemias and resistance mechanisms to targeted therapies
TARGETMOL CHEMICALS INC KW-2449 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. KW-2449 is a multiple-targeted inhibitor mostly for Flt3 (IC50 6.6 nM) modestly effective to Bcr-Abl FGFR1 and Aurora A; little inhibitory on PDGFR(beta) IGF-1R EGFR. purity: 99%
Medchemexpress LLC CAY 10465 | 688348-33-6 | 98.3% | 317.13 | 1 ML
CAY 10465 is a selective and high-affinity AhR agonist with a Ki of 0.2 nM. It demonstrates no effect on the estrogen receptor (Ki >100000 nM). This compound reduces apolipoprotein A-I (apo A-I) levels in HepG2 cells and inhibits the synthesis of the protein.
- Selective and high-affinity AhR agonist
- No effect on estrogen receptor
- Reduces apolipoprotein A-I levels in HepG2 cells
- Inhibits protein synthesis
Ambeed N1 N1 N2 N2Tetramethyldiazene1
N1,N1,N2,N2-Tetramethyldiazene-1,2-dicarboxamide, 10465-78-8, 97%
![Medchemexpress LLC {4-[(E)-2-(1H-indazol-3-yl)vinyl]phenyl}(1-piperazinyl)methanone | 1000669-72-6 | MFCD18385006 | 99.9% | 332.40 g·mol⁻¹ | C20H20N4O | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000244741.png-250.jpg)
Medchemexpress LLC {4-[(E)-2-(1H-indazol-3-yl)vinyl]phenyl}(1-piperazinyl)methanone | 1000669-72-6 | MFCD18385006 | 99.9% | 332.40 g·mol⁻¹ | C20H20N4O | 1 ML
KW-2449 is a multi-targeted small-molecule kinase inhibitor active against FLT3, ABL (including ABL T315I), and Aurora kinases. It exhibits low-nanomolar potency and is supplied for laboratory research use.
- Multi-targeted kinase inhibitor effective against FLT3, ABL, and Aurora kinases.
- Low-nanomolar potency with reported IC50s of 6.6, 14, 4, and 48 nM (FLT3, ABL, ABL T315I, Aurora).
- Provided as a 10 mM solution in DMSO (1 mL) or as a solid in multiple milligram sizes.
- High purity suitable for research (reported purity 99.9%).
- Molecular formula C20H20N4O; molecular weight 332.40 g·mol⁻¹.
- For research use only; not for human or veterinary use.
Aobchem 2-Chloro-6-fluoro-3-methylbenzaldehyde | 97% | CAS 104451-99-2 | C8H6ClFO | 1kg
2-Chloro-6-fluoro-3-methylbenzaldehyde | 97% | CAS 104451-99-2 | C8H6ClFO | 1kg
Aobchem 1-Fluoro-3-ethoxy-5-methylbenzene | ≥97% | CAS 1809158-02-8 | C9H11FO | 1g
1-Fluoro-3-ethoxy-5-methylbenzene | ≥97% | CAS 1809158-02-8 | C9H11FO | 1g
Aobchem 2-Chloro-5-fluoro-4-methylbenzoic acid | ≥97% | CAS 103877-61-8 | C8H6ClFO2 | 500mg
2-Chloro-5-fluoro-4-methylbenzoic acid | ≥97% | CAS 103877-61-8 | C8H6ClFO2 | 500mg
Aobchem 2-Bromo-6-hydroxy-4-methylbenzaldehyde | 95% | CAS 139976-21-9 | C8H7BrO2 | 1g
2-Bromo-6-hydroxy-4-methylbenzaldehyde | 95% | CAS 139976-21-9 | C8H7BrO2 | 1g
Aobchem 2-Bromo- -ethenyl-4-methylbenzenemethanol | 95% | CAS 1554051-90-9 | C10H11BrO | 250mg
2-Bromo- -ethenyl-4-methylbenzenemethanol | 95% | CAS 1554051-90-9 | C10H11BrO | 250mg